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Type-2 Diabetes Mellitus

What is Type-2 Diabetes Mellitus (T2DM)?

Diabetes is a metabolic disorder characterized by high blood sugar, or hyperglycemia.  There are three main forms of diabetes: Type-1, Type-2, and Gestational diabetes.  These three forms have similar signs, symptoms, and consequences, but are rooted in different causes.

Type-1 Diabetes is an incurable chronic condition.  It is usually due to the auto-immune destruction of insulin producing cells (pancreatic beta cells).  It is also the number one cause of childhood diabetes.

Type-2 Diabetes results from a tissue-wide resistance to insulin, and can progress to loss of beta cell function.  It is also an incurable chronic condition.  

Similar to Type-2 Diabetes, Gestational Diabetes also involves insulin resistance. Occurring in women that are genetically predisposed to developing the condition, insulin resistance is brought on by the hormones of pregnancy.  It typically resolves upon delivery.  

Diabetes can cause many complications.  Some of the serious long-term complications are cardiovascular disease, heart disease, and kidney disease.  As well, diabetics can develop chronic renal failure, and the most significant cause of adult blindness in the non-elderly is diabetes-related retinal failure.  Nerve damage and micro-vascular damage are also complications which can result in erectile dysfunction and poor healing.  The leading cause of non-traumatic amputation in adults is the poor healing of wounds seen in long-term diabetes sufferers.  Adequate treatment of diabetes, as well as increased emphasis on blood pressure control, and leading a healthy lifestyle can improve the risk profile of most of the above complications.

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Symptoms:

Since the symptoms of diabetes seem relatively harmless, diabetes often goes undiagnosed.  However, early detection of diabetes symptoms is key in lowering the chances of developing the complications associated with diabetes.  

Symptoms include:

1.      Frequent urination

2.      Excessive thirst

3.      Extreme hunger

4.      Unusual weight loss

5.      Increased fatigue

6.      Irritability

7.      Blurry vision

 

Do you know someone who has Type-2 Diabetes Mellitus (T2DM)?

     UCRT is participating in a clinical research trial for a study drug looking at individuals with mild to moderate Type-2 Diabetes Mellitus.  Qualified participants will receive study-related evaluations, lab work, electrocardiograms, and doctor’s consultation at no charge while taking part in the study.

Eligible participants must:

  • Be male or female, at least 18 years of age
  • Be diagnosed with mild to moderate Type-2 Diabetes Mellitus
  • Is taking only metformin to treat their diabetes
  • Has been taking metformin for at least 3 months

     If someone you know has Type-2 Diabetes Mellitus and you think they meet the above criteria for eligibility to enrol in this study, please contact us at Universal Clinical Research & Technology (UCRT) at 407.574-3801 or 407.574-7361.

     For more information on this and other clinical studies, please call Garry or Marla at 407-574-3801.

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